Solvent Deterget Virus Inactivated Plasma

SD plasma is critical for assiting transfusional medicine and therapies for IgG using COVID-19 plasma from naturally immunized patients. Solvent/detergent-treated plasma (SD-plasma) has been developed in order to reduce the risks associated with the use of untreated FFP. Solvent/detergent technology virtually eliminates the risk of transmission of enveloped viruses, such as human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV). The SD-plasma manufacturing process, which involves pooling hundreds of single-donor plasma units, reduces the virus load through dilution and neutralizing antibodies present in the plasma pool, lowers the antibody titres against blood cells and plasma proteins, and allows a more standardized content of plasma proteins.